The strike was carried out by a jet-powered drone against one of the platforms where train No. 866 from Dnipro to Zaporizhzhia was standing, Ukraine's state railway operator Ukrzaliznytsia said. People remained on the platform despite an air-raid warning, the company said.
Oleksandr Hanzha, head of the Dnipropetrovsk regional military administration, said 13 people were killed and five injured in the daytime attack on the station.
All emergency services are working at the scene.